Plaquenil (hydroxychloroquine) is an effective medication for autoimmune conditions and malaria that comes with less side effects than other DMARDs. I started both of these ten weeks ago, I'm on 400mg hydroxy and 25mg of methotrexate. Plaquenil tablets prospect Coming off hydroxychloroquine I am on both methotrexate and plaquenil. I have been on plaquenil for over a year and a half and methotrexate since September. I have had no side effects from either one. I get my eyes checked every six months and I am now at once a month on blood work for my liver enzymes used to be every 2 weeks. Hydroxychloroquine is a quinoline medicine used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Hydroxychloroquine is in a class of drugs called antimalarials. It is used to prevent and treat acute attacks of malaria. It is also used to treat discoid or systemic lupus erythematosus and rheumatoid arthritis in patients whose symptoms have not improved with other treatments. I don't know how I can carry on like this feeling constantly sick and anxious :-( Does it get better? I started both of these ten weeks ago, I'm on 400mg hydroxy and 25mg of methotrexate. Last week I got in such a state about having to take them and it's got to a point where I constantly feel sick because I'm so anxious of having them, so I've been taken off hydroxychloroquine for two weeks so that now I only have medication on a Monday, I thought this would help but the whole afternoon I was feeling nauseuous and now I've taken my weekly dose my stomach is swirling and head is pounding. Hydroxychloroquine & methotrexate Rheumatoid Arthritis Treatment Options Johns Hopkins., Hydroxychloroquine Uses, Dosage & Side Effects - Apteka internetowa plaquenilPlaquenil and eye painKikuchi-fujimoto disease hydroxychloroquine as a treatmentHow does plaquenil help inflammationPlaquenil tablets 200mg Hydroxychloroquine is a disease-modifying anti-rheumatic drug DMARD approved for adults with RA. It is often given in combination with methotrexate and sulfasalazine a treatment known as triple therapy, to help slow RA disease progression for patients who do not get relief from methotrexate therapy alone. Hydroxychloroquine Plaquenil. Hydroxychloroquine MedlinePlus Drug Information. Hydroxychloroquine oral and methotrexate sodium oral Drug.. OBJECTIVE To examine the bioavailability of methotrexate MTX in the presence of hydroxychloroquine HCQ, and vice versa, to determine a possible pharmacokinetic explanation for the observation that combination treatment of rheumatoid arthritis with MTX and HCQ has been shown, clinically, to be more potent than MTX used alone. Plaquenil hydroxychloroquine is an effective medication for autoimmune conditions and malaria that comes with less side effects than other DMARDs. Otrexup methotrexate is the first-choice treatment for many types of cancer and arthritis, but it has many side effects. Hello hope everyone is well just a quick question, i have been on methotrexate for 2 months increasing from 7.5 to 15 and now to 25mg.weekly now been given plaquenil 400mg daily, has anyone else been on this mixture and has it worked or how long should i wait to see if it works.