The toxicities can be grouped into categories such as pigmentary retinopathies, crystalline retinopathies, retinal vasculopathies, and retinopathies characterized by retinal edema or folds. Here we present a case of topiramate (Topamax, Ortho-Mc Neil Neurologics) causing transient angle closure and retinal folds. Hydroxychloroquine retinopathy cumulative dose Can methrotrexate be taken with plaquenile Hydroxychloroquine sulfate HCQ, Plaquenil is an analogue of chloroquine CQ, an antimalarial agent, used for the treatment of systemic lupus erythematosus, rheumatoid arthritis and other autoimmune disorders. Its use has been associated with severe retinal toxicity, requiring a discontinuation of therapy. Plaquenil hydroxychloroquine is a medicine commonly used to treat patients with systemic lupus erythematosus and rheumatoid arthritis. After prolonged use, it can sometimes damage the macula and cause central vision loss. Typically, the macula loses its orange pigment, giving the appearance of a bullseye. Download PDF. Drug-induced ocular side effects are back in the spotlight, thanks to the Academy’s revision of its recommendations on screening for retinal toxicity from chloroquine and its analogue hydroxychloroquine Plaquenil. 1 There are hundreds of drugs with potential retinal toxicity—so many that the National Registry of Drug-Induced Ocular Side Effects doesn’t stratify them by. A 26-year-old woman reported to the emergency room with a chief complaint of sudden, painless loss of vision in both eyes. We follow with a review of the literature regarding topiramate toxicity, as well as a brief review of the other major categories of pharmacologic retinal toxicity. Plaquenil induced retinal toxicity Has anyone experienced plaquenil toxicity with damage to eyes?, Plaquenil Toxicity - Bennett & Bloom Eye Centers Is plaquenil quinineHow effective is plaquenilChloroquine raynaudsPlaquenil mg The risk of retinal toxicity secondary to hydroxychloroquine can be divided into dose-related and patient-related factors. For the former, it is the maximum daily dosage 400 mg/day, the cumulative dose 1000 g, and the duration of treatment 5 years that appear to be the most important determinants of the risk of toxicity 3. A Case of Severe Hydroxychloroquine-Induced Retinal Toxicity.. Rx Side Effects New Plaquenil Guidelines and More.. A Case of Severe Hydroxychloroquine-Induced Retinal.. Plaquenil induced retinal toxicity is reversible if detected early and plaquenil dosage altered or the medication discontinued. Even suspicious early plaquenil toxicity warrants communication with the patient’s treating physician, and meaningful coordination of care would include a report even if the findings are normal. Review of Optometry presents Retina Revealed Case Studies. Plaquenil Induced Retinal Toxicity The side effect that is of greatest concern is retinal toxicity. Retinal toxicity of Plaquenil may manifest itself with subtle disturbances of the retinal pigment epithelium which may eventually lead to complete destruction of the macula in the form of bull’s-eye maculopathy.