Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Hydroxychloroquine discontinue Hydroxychloroquine sulfate dosage for lupus Plaquenil hydroxychloroquine "When first diagnosed 3 yrs ago, my rheumy wanted to try Plaquenil first. He did tell me that some people develop allergies to the drug. Sure enough, three months in I developed hives all over my body. Had to stop the drug. Now I have Kenalog injections every 5-6 months which have worked well for me. Three anti-malarial drugs are prescribed for lupus symptoms. Hydroxychloroquine Plaquenil is the most commonly prescribed because it is generally believed to cause fewer side effects; chloroquine Aralen has a reputation for more serious side effects, but it may be prescribed in situations where hydroxychloroquine cannot be used. I can only speak for myself and my personal experience. Plaquenil has helped me on many levels on many days. I think, for me, anyway, the depression and anxiety I often feel is due to the autoimmune issues/sjogrens. I have not noticed an increase in depression/anxiety since being on the plaquenil but that is just me. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Hydroxychloroquine makes me feel worse When starting hydroxychloroquine do symptoms feel., Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus Center Malaria treatment chloroquine how many dailyPlaquenil icd 10 codeChloroquine and jnk inhibitor clinical trialChloroquine purchase online Went like this back and forth and it was definitely the medicine. Also I started to feel worse while taking it. It could be that the weather is getting colder and that always makes me feel worse. but we decided I couldn't tolerate an increase in dosage which was what would have been next on the treatment plan so we moved on to something else. User Reviews for Hydroxychloroquine to treat. -. Plaquenil causing mood changes and depression?. Hydroxychloroquine Reviews Everyday Health. Thanks. for the info. i feel so so so bad. It has been going on for years but it seems worse since spring/summer started. my ra factor has been negative. the only thing coming back postive at this point is my ANA which i believe is speckled & homogenous. The first rheum wrote me off and told me I had nothing,this was 2004! In fact, one of my symptoms was hair loss. Since taking hydroxychloroquine fun to say and fun to spell. my hair loss has stopped and I’ve had some regrowth. My skin doesn’t turn grey in the sun, but I am more prone to burning so stick to the shade or sunblock. My dark hair hasn’t bleached either Methylfolate Makes Depression Worse For Me – Now What? Don’t worry – you have a couple of options. If you’re sure this isn’t just your body adjusting to methylfolate the symptoms last beyond the first week of moderate supplementation then it’s time to check to see if you fit the profile of an undermethylator. If that sounds like.