Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Maqular degeneration plaquenil Chloroquine mechanism of action ppt Hydroxychloroquine 200 mg para que se usa Incidence of retinal toxicity from plaquenil Recommendations on Screening for Chloroquine and Hydroxychloroquine Retinopathy Retinal toxicity from chloroquine CQ and its analogue, hydroxychloroquine HCQ, has been recognized for many years. Chloroquine toxicity remains a problem in many parts of the world, but is seen less frequently in the United States where the drug largely has been replaced by HCQ. Diagnosis Hydroxychloroquine-induced retinal toxicity Discussion. Chloroquine CQ and hydroxychloroquine Plaquenil HCQ have been used for many years, initially for the treatment of malaria but now more commonly for the treatment of inflammatory diseases such as rheumatoid arthritis and lupus 1. It is now considered for new disease applications in diabetes, heart disease and adjunct cancer therapies 2. The majority of patients with SLE in the USA have been prescribed hydroxychloroquine HCQ. Given more recent guidelines, the availability of only one strength 200 mg tablets may limit the flexibility and ability to accurately dose patients with lupus. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Splitting hydroxychloroquine Plaquenil Drug and Medication User Reviews on RxList, Hydroxychloroquine Plaquenil Toxicity and. Hydroxychloroquine sulphate mechanism of actionHydroxychloroquine and acetaminophenPlaquenil diagnosis Plaquenil hydroxychloroquine belongs to a group of medicines called quinolines. Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Plaquenil Uses, Dosage & Side Effects -. Hydroxychloroquine usage in US patients, their experiences.. Hydroxychloroquine Plaquenil Toxicity and Recommendations.. Don’t split your pills with a knife. Studies show that doing so too often leads to unequal halves. Pills should only be split in half, not into smaller portions, such as thirds or quarters. The easiest pills to split are relatively flat round ones with a scored center. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Hydroxychloroquine HCQ is nearly identical in structure to CQ and has a similar mechanism of action and therapeutic efficacy in rheumatological and infectious diseases. Like CQ, it also has a long half-life, and a very high volume of distribution.