While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners. Hi, I was diagnosed with RA and was put on sulfa, my rheumy tried adding mtx but i had awful side effects so am now on hydroxychloroquine and sulfa..this combination worked for anyone? Hi I've been on this combination for a few months and unfortunately it hasn't worked for me - but that's not to say it won't for you, we are all different in how we react to drugs. Sulphasalasine was helpful in my case but took 12 weeks to kick in. Hydroxychloroquine plaquenil motrin What is the chemical name for plaquenil Sulfasalazine works by slowing the radiographic progression damage to the joints of rheumatoid arthritis, and reducing pain and swelling. It is one of the first line treatments for moderate to severe rheumatoid arthritis, along with methotrexate and leuflunomide arava. This article primarily covers the author's experience with the use of the combination of methotrexate MTX, sulfasalazine SSZ, and hydroxychloroquine HCQ to treat patients with rheumatoid arthritis RA. Sulfasalazine is a disease-modifying anti-rheumatic drug DMARD indicated for the treatment of adults and children over 6 with RA who have not responded to non-steroidal anti-inflammatory drugs NSAIDs. DMARDS decrease the pain and swelling of inflammatory arthritis and may also prevent damage to joints. I'm about to start MTX & am hoping that I wont have side effects with that! The side effects of the methotrexate for me were horrendous (chronic chest infections) and I'm now asthmatic as a result. I've stopped Sulfa as I was experiencing a bad taste & smell, which may be caused by sulfa. After a while it wasn't as effective and I too was prescribed methotrexate alongside. Sulfasalazine and hydroxychloroquine rheumatoid arthritis Sulfasalazine and Plaquenil drug interactions - eHealthMe, TRIPLE THERAPY WITH METHOTREXATE, SULFASALAZINE, AND. Rash with hydroxychloroquinePlaquenil and cellceptHydroxychloroquine lupus side effectsChloroquine dna transfection Although rheumatoid arthritis is generally an inflammatory process of the synovium, structural or mechanical derangement is a frequent cause of pain or loss of joint function. Pain and joint mobility may be improved by a surgical approach. Rheumatoid Arthritis Treatment Options Johns Hopkins.. Sulfasalazine for Rheumatoid Arthritis.. REFERENCES - UpToDate. Hi, I was diagnosed with RA and was put on sulfa, my rheumy tried adding mtx but i had awful side effects so am now on hydroxychloroquine and sulfa.this combination worked for anyone? just wondered how other people got on with it. Hydroxychloroquine Plaquenil and sulfasalazine Azulfidine are used for mild rheumatoid arthritis. They are not as powerful as other disease-modifying antirheumatic drugs, but they usually cause fewer side effects. Combination hydroxychloroquine and sulfasalazine - does it work for any of you. Now adding sulfasalazine hydroxychloroquine. Content on HealthUnlocked does.