No matter what kind of medicine you take, whether OTC (over-the-counter) or prescription, it is destined to take a trip through your kidneys. Taking a drug the wrong way or in excessive amounts can damage these vital, bean-shaped organs and lead to serious complications. In the worst-case scenario, it could necessitate a kidney transplant.“Compared with 30 years ago, patients today…have a higher incidence of diabetes and cardiovascular disease, take multiple medications, and are exposed to more diagnostic and therapeutic procedures with the potential to harm kidney function,” according to Cynthia A. Naughton, Pharm D, senior associate dean and associate professor in the department of pharmacy practice at North Dakota State University. All of these factors are associated with an elevated risk of kidney damage. An estimated 20% of cases of acute kidney failure are due to medications. The technical term for this scenario is “nephrotoxicity,” which is growing more common as the aging population grows, along with rates of various diseases. A dosage of 1 g of valacyclovir 3 times per day (TID) for 7 days has already been shown to be superior to an oral dosage of 800 mg acyclovir 5 times per day for 7 days in immunocompetent individuals. The objective of this study was to assess the safety and efficacy of an oral dosage of valacyclovir, 1 g TID versus 2 g TID, for the treatment of herpes zoster in immunocompromised patients ⩾18 years of age. The oral dosage schedule of 2 g of valacyclovir TID reaches acyclovir plasma levels similar to those achieved with intravenous acyclovir therapy given to immunocompromised patients (10 mg/kg every 8 h for 7 days). In this double-blind study, 87 immunocompromised patients with clinical evidence of localized herpes zoster were randomized to receive oral valacyclovir therapy for 7 days, either 1 g TID or 2 g TID, within 72 h after onset of zoster rash. Patients were seen and assessed for cutaneous healing, zoster-associated pain (ZAP), and/or zoster-associated abnormal sensations (ZAAS), up to 24 weeks. Participants in both arms of the study demonstrated similar median times to full crusting of the rash (8 days), and both dosages were safe and effective therapies for reduction of ZAP and ZAAS in the immunocompromised patient population Trials registration Clinical identifier: NCT00006131 Herpes zoster, or shingles, is a common disease caused by a reactivation of the varicella-zoster virus (VZV). Subsequent to primary VZV infection (i.e., chickenpox), the virus lies latent in the dorsal root ganglia, and reactivation can occur at any age [1, 2]. Doxycycline how long to work Sertraline constipation Valtrex does not prevent the spread of herpes, so take precautions to protect. Although rare, Valtrex can cause a life-threatening disorder that. Detailed drug Information for Valtrex. Includes common brand names, drug descriptions, warnings, side effects and dosing information. The latest Tweets from MSU @michiganstateu. The official Twitter account for Michigan State University. #SpartansWill. East Lansing, MI USA Valacyclovir is used to treat herpes zoster (shingles) and genital herpes. It does not cure herpes infections but decreases pain and itching, helps sores to heal, and prevents new ones from forming. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information. It is usually taken every 8 hours (three times a day) for 7 days to treat shingles. To treat genital herpes it is usually taken twice a day for 5 days. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Do not take more or less of it or take it more often than prescribed by your doctor. Use this medication as soon as possible after symptoms appear. Continue to take valacyclovir even if you feel well. Please complete all the fields below to send the bad drug report. Each field is required to be completed in order to send. The submission of this form does not form an attorney client relationship. An attorney client relationship will only be formed after the execution and return of a retainer agreement. Valtrex may decrease kidney function, especially when combined with other drugs. When used along with other kidney damaging medications, Valtrex can be extremely dangerous. The following may be harmful to the kidneys: Valtrex is an FDA pregnancy Category B drug. Does valtrex cause constipation Valtrex Side Effects in Detail -, Valtrex Advanced Patient Information - Buy viagra per pillClonidine for sleep aid Service d'installation de portes et fenêtres - Nos professionnels effectuent l’installation de vos portes et fenêtres dans un environnement sécuritaire, Installation de portes et fenêtres - Service offert par Solaris.. MSU @michiganstateu Twitter. Valtrex - Uses, Side Effects, Interactions -. Drug Information on Valtrex valacyclovir includes drug pictures, side effects, drug interactions. Valacyclovir is used to treat infections caused by herpes viruses, including genital. Do not give this medicine to a child without medical advice. Medical Editor John P. Cunha, DO, FACOEP. Our Valtrex Side Effects Drug Center provides a comprehensive view of available drug information on the. Tap along the timeline to move to different parts of the audio file. ChemoExperts Tips. Bortezomib can cause reactivation of herpes HSV- herpes simplex virus or.