I currently take 6 tablets a week and I started taking them in February this year . Has anyone been through the same as me, and find that the meds simply haven't worked so you have to simply start again. I have called my nurse specialist but she hasn't got back yet. Hang in there- it's very early days x I'm afraid Jacki08 is right it's early days and these meds take time. I am still in a lot of pain I have immense fatigue and feel miserable. I started MTX in September along with naproxen and gradually built up to 8 tablets (20mg) a week by the end of December. Taking hydroxychloroquine Stopping plaquenil change to what Mar 17, 2019 Hydroxychloroquine is a quinoline medicine used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Oct 22, 2009 There are pros and cons for all of them and it's a matter of finding one that suits and one that doesn't give you any intolerable side effects. Make sure you take them on a full stomach. Your doc would help you work out which one might be best for you based on your individual circumstances. Hydroxychloroquine brand namePlaquenil is a disease-modifying anti-rheumatic drug DMARD approved for adults with RA. It is often given in combination with methotrexate and sulfasalazine a treatment known as triple therapy, to help slow RA disease progression for patients who do not get relief from methotrexate therapy alone. 1,2. Research shows that this medication reduces RA symptoms. Things have been in their stride since mid February and now it's looking good regarding fatigue, swelling and pain (though I only ever had a little pain compared to what others have described). I started taking mthx in October last year and expected results quite quickly. What if hydroxychloroquine doesn t work Hydroxychloroquine information booklet - Versus Arthritis, If Plaquenil doesn't work. Lupus Forums at The Lupus Site Plaquenil and neurotransmitter acetylcholine Does anyone know if hydroxychloroquine and methotrexate can cause weight loss day, been taking for over a year now but although it helps with some of the pain. I have to have steroid. Does anyone take methotrexate and hydroxychloroquine. - NRAS. Hydroxychloroquine Plaquenil -. Taking Plaquenil for Rheumatoid Arthritis. Switching medicines when one doesn’t work is an important therapeutic strategy that rheumatologist and patients can use in an attempt to keep the disease at bay. In an earlier post, I discussed strategies for knowing when it may be time to switch RA treatments. Hydroxychloroquine comes as a tablet to take by mouth. For prevention of malaria in adults, two tablets are usually taken once a week on exactly the same day of each week. The first dose is taken 1 to 2 weeks before traveling to an area where malaria is common, and then doses are continued for 8 weeks after exposure. Hydroxychloroquine Plaquenil, chloroquine Aralen, and quinacrine Atabrine are medications that were originally used to prevent or treat malaria. However, during World War II it was also found that these medications were effective in treating the symptoms of lupus.