They are most common among people with weak immune systems. People with certain health conditions may need to take medications with side effects that can weaken your immune system and put you at risk for fungal infections. Pharmacokinetics chloroquine mice Chloroquine work in the body gov I doubt it is the Plaquenil affecting your immune system, but the actual Lupus itself as it can affects the white blood cells and lower them so we get every infection going. You need to speak to your rheumy for more clarification in your case. Any one have any experience or info regarding pre-existing precancerous conditions and the effects of Plaquenil on the immune system. I see so much info on the net where some says that Plaquenil has very mild effect on immune system except for eye issues --- Other info says it is an immunosuppressant. Nov 15, 2016 I have been taking Plaquenil hydroxychloroquine for about 10 months. Since August I’ve had some strange infections. First I got shingles. Then I started with a bacterial vaginosis. I discontinued the Plaquenil for about a week when I was diagnosed with shingles and I thought it may have helped it not be so bad. The bacterial vaginosis just won’t go away. I use metro gel and it’s goes. Fungal infections can range from mild to life-threatening. Specifically, corticosteroids and TNF (tumor necrosis factor) inhibitors are two types of medications that can increase your chances of getting a fungal infection. How does plaquenil work on the immune system Do either hydroxychol/Plaquenil put you at risk for greater., Plaquenil and its affect on the immune system DailyStrength Plaquenil and sleep apnea Higher doses of medications that weaken your immune system are more likely to increase your risk of getting a fungal infection. 5,11,13,14. Click on the sections below to see lists of corticosteroids and TNF inhibitors that can increase the chances of getting a fungal infection. Medications that Weaken Your Immune System and Fungal.. Does Plaquenil hydroxychloroquine impact my immune system.. Anyone on Hydroxychloroquine plaquenil - Autoimmune.. Today, Plaquenil and other antimalarials are also used to treat and help prevent symptoms caused by certain autoimmune diseases such as rheumatoid arthritis RA, systemic lupus erythematosus, and discoid lupus, even though these diseases are not caused by malaria parasites. Plaquenil and Immune system disorder - from FDA reports Summary Immune system disorder is found among people who take Plaquenil, especially for people who are female, 50-59 old, have been taking the drug for 5 - 10 years, also take medication Enbrel, and have Pain. Feb 19, 2020 SIDE EFFECTS. The following adverse reactions have been identified during post-approval use of PLAQUENIL or other 4-aminoqunoline compounds. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.