Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Hydroxychloroquin Chloroquine mechanism mitochondria Can you take plaquenil with flagyl Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Stop taking hydroxychloroquine and call your doctor at once if you have trouble focusing, if you see light streaks or flashes in your vision, or if you notice any swelling or color changes in your eyes. The usual dosage works for most people who take Plaquenil, but it is possible to increase or decrease the dose based on individual needs. It's important to watch for possible side effects and toxicity. For people who weigh less than 80 kg, a lower daily dose is prescribed, up to a maximum of 5 mg/kg of body weight. If you are also taking kaolin or antacids, take them at least 4 hours before or after using hydroxychloroquine. Dosing. The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Taking plaquenil high dose Stopping plaquenil. DailyStrength, Taking Plaquenil for Rheumatoid Arthritis Rheumatoid arthritis methotrexate therapy hydroxychloroquine monotherapy Take Plaquenil EXACTLY as prescribed by your physician. Do not stop taking the medication without first speaking to your doctor. Taking Hydroxychloroquine with food and/or milk can help prevent stomach upset. If you miss a dose, take it as soon as you remember. Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus. Hydroxychloroquine Oral Route Proper Use - Mayo Clinic. Rheumatoid Arthritis Treatment Options Johns Hopkins.. In rare cases, hydroxychloroquine can cause visual changes or loss of vision. Such vision problems are more likely to occur in individuals taking high doses for many years, individuals 60 years or older, or those with significant kidney disease. At the recommended dose, development of visual problems due to the medication is rare. Aug 14, 2017 Plaquenil is the brand name of hydroxychloroquine, a drug used to prevent or treat malaria. Plaquenil can cause serious side effects when used in high doses for chronic diseases such as RA over the long term. Ventricular arrhythmias and torsade de pointes TdP have been reported with the use of hydroxychloroquine. At high doses, loperamide has been associated with serious cardiac toxicities, including syncope, ventricular tachycardia, QT prolongation, TdP, and cardiac arrest.