Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Plaquenil and tinazidole Plaquenil cause low blood pressure Hydroxychloroquine is a prescription medication used to reduce pain and swelling caused by diseases of the immune system such as rheumatoid arthritis, juvenile arthritis, and systemic lupus erythematosus SLE. This medication belongs to a group of drugs called DMARDs disease modifying antirheumatic drugs which work by suppressing the excessive activity of the immune system. Rheumatoid Arthritis. The action of hydroxychloroquine is cumulative and may require weeks to months to achieve the maximum therapeutic effect see CLINICAL PHARMACOLOGY. Initial adult dosage 400 mg to 600 mg 310 to 465 mg base daily, administered as a single daily dose or in two divided doses. In a small percentage of patients, side effects may require temporary reduction of the initial. Moved Permanently. The document has moved here. Hydroxychloroquine may also be used for purposes not listed in this medication guide. Hydroxychloroquine is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Hydroxychloroquine sulphate overdose Hydroxychloroquine MedlinePlus Drug Information, Plaquenil Dosage Guide - Hydroxychloroquine blindChloroquine aralen drug card If OVERDOSE is suspected If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened. How do I store and/or throw out Hydroxychloroquine? Store at room temperature. Protect from light. Store in a dry place. Hydroxychloroquine Indications, Side Effects, Warnings.. Gov. A case of fatal hydroxychloroquine overdose. Hydroxychloroquine is a quinoline medicine used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Hydroxychloroquine can lower the seizure threshold; therefore, the activity of antiepileptic drugs may be impaired with concomitant use. Azithromycin Major Avoid coadministration of hydroxychloroquine and azithromycin. Hydroxychloroquine increases the QT interval and should not be administered with other drugs known to prolong the QT interval. Annual screening may be commenced before 5 years of treatment if additional risk factors for retinal toxicity exist, such as concomitant tamoxifen therapy, impaired renal function eGFR less than 60 mL/minute/1.73 m 2 or high-dose therapy greater than 5 mg/kg/day of hydroxychloroquine sulfate.