Drug interactions are reported among people who take Xanax and Caffeine together. (latest outcomes from Xanax 103,173 users) Caffeine has active ingredients of caffeine. (latest outcomes from Caffeine 2,054 users) Female: NOTE: The study is based on active ingredients and brand name. This study is created by e Health Me based on reports of 47 people who take Xanax and Caffeine from FDA, and is updated regularly. Other drugs that have the same active ingredients (e.g. WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health. DISCLAIMER: All material available on e Health is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the e Health Me site and its content is at your own risk. My opiion too which sucks so fucking bad because i love coffee and tea and cacao.........i CANT STAND the effects of methylxanthines on me and i definatly feel my benzos NOT. its wierd because meth doesnt do any of that to me, and it gets along jsut fine with my kpines. well adderall seemed to get along jsut fine with it tonight as well. Back in the day...i used to drink a rockstar energy drink and take 1mg of xanax and feel pretty damn good. I havent tried this in a long ass time, but it was aight back in the day. I try to stay away from xanax nowadays It's fine, it somewhat works. I've taken a few different kinds of benzos with a bunch of coffee, and you do get the sense of well being still, but with less fatigue. 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