Azithromycin has become a frequent choice for the treatment of group A streptococcal (GAS) tonsillopharyngitis. In this study, our objective was to determine the optimal dose of azithromycin for treatment of GAS tonsillopharyngitis in children and adults by analyzing trials that used different dose regimens. We performed a meta-analysis of randomized, controlled trials that involved bacteriological confirmation of GAS tonsillopharyngitis, random assignment to receive either azithromycin or a 10-day comparator antibiotic, and assessment of bacteriological eradication by throat culture after therapy. The primary outcomes of interest were bacteriological and clinical cure rates. Nineteen trials involving 4626 patients were included in the analysis. One trial used 10-day course of 2 different comparator antibiotics, and 2 trials compared 2 dose regimens of azithromycin with a 10-day course of comparator antibiotic; all other trials compared 1 dose regimen of azithromycin with a single 10-day course of comparator antibiotic. In children, azithromycin administered at 60 mg/kg per course was superior to the 10-day courses of comparators ( = .14); 5-day regimens were inferior to 3-day regimens (P=.006). I always thought that Viagra is a creation of woman-haters! Why should men get all the advantages and even the drug boosting their potency and we, women, are deprived of the attention of sexologists?! And finally justice is obtained - they hit upon an idea of creation of an appropriate drug for women! Or may be that was a woman who invented this medicine?! Anyway I'm completely satisfied with the way it works! I have always been a man of a young heart and good cheer. 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This is the major advantage of azithromycin. The usual dose is 500 mg the first day then 250 mg daily for four more days for an adult. Streptococcal pharyngitis or “strep throat” occurs when a certain type of bacterial infection causes the tissues at the back of your mouth and throat to become inflamed, irritated and sore. It is caused by a bacteria called group A streptococcus or GAS. Unlike most other common causes of sore throat, strep throat is treated with a course of antibiotics to fight the infection and prevent rare complications. Strep throat can occur at any age but is most common among children and young adults. Infection rates peak during the late fall, winter and early spring. Strep throat is contagious and can be spread amongst individuals having close contact such as family members or those in a school or daycare setting. The most frequently reported symptoms of strep throat include throat pain, red swollen tonsils, whitish patches at the back of the throat, pain or difficulty with swallowing, swollen tender lymph nodes (glands) in the neck and fever. Azithromycin has relatively broad but shallow antibacterial activity. It inhibits some Gram-positive bacteria, some Gram-negative bacteria, and many atypical bacteria. A strain of gonorrhea reported to be highly resistant to azithromycin was found in the population in 2015. Neisseria gonorrhoeae is normally susceptible to azithromycin, Safety of the medication during breastfeeding is unclear. It has been reported that because only low levels are found in breastmilk and the medication has also been used in young children, it is unlikely that breastfed infants would suffer adverse effects. Most common adverse effects are diarrhea (5%), nausea (3%), abdominal pain (3%), and vomiting. Fewer than 1% of people stop taking the drug due to side effects. 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Recent safety concerns regarding azithromycin have raised alarm about this agent's role with pneumonia. We sought to clarify the relationship between. March 2017 Best Antibiotics for Strep Throat The Best Antibiotics for Strep Throat. Streptococcal pharyngitis or “strep throat” occurs when a certain type of bacterial infection causes the tissues at the back of your mouth and throat to become inflamed, irritated and sore.