Pattern of Retinopathy: Although the locus of toxic damage is parafoveal in many eyes, Asian patients often show an extramacular pattern of damage. Dose: We recommend a maximum daily HCQ use of 5.0 mg/kg real weight, which correlates better with risk than ideal weight. Can you take doxe-pin hcl and hydroxychloroquine 200 mg to Plaquenil in ana pregnancy Plaquenil liver failure Find user ratings and reviews for Plaquenil oral on WebMD including side effects and drug interactions, medication effectiveness, ease of use and satisfaction The main outcomes were toxicity as determined by characteristic visual field loss or retinal thinning and photoreceptor damage. They also examined risk factors and prevalence. The study findings revealed that when hydroxychloroquine was used at doses 5mg /kg, the risk of retinopathy was 1% in the first 5 yrs. 2% in 10 yrs. 20 % after 20 yrs. Humphrey Visual Field 10-2 is sensitive at detecting subtle paracentral visual field defects and is recommended during all screening visits. SITA testing with pattern deviation plots is recommended. Wider test patterns 24-2 or 30-2 are needed for Asian patients due to the possibility of extra-macular manifestations of toxicity. Risk of Toxicity: The risk of toxicity is dependent on daily dose and duration of use. There are no similar demographic data for CQ, but dose comparisons in older literature suggest using 2.3 mg/kg real weight. Plaquenil and visual field testing Plaquenil Side Effects on Your Eyes and Vision, My Take on New Ocular Screening Guidelines for Plaquenil. Hydroxychloroquine increase metroxtratePlaquenil tooth decayDoes fibromyalgia respond to plaquenil Paracentral scotomas have been reported prior to the associated maculopathy, so an amsler grid test or central 10-2 visual field perimetry was recommended. 2,5. Additionally, color vision––helping in the assessment of macular integrity––was recommended as an optional test. New Plaquenil Guidelines. Hydroxychloroquine Plaquenil Toxicity and.. Plaquenil and failed vision test?. Macular Society Eye screening for patients taking hydroxychloroquine. Hydroxychloroquine is a medication used to treat several conditions including rheumatoid arthritis, systemic lupus erythematosus, some skin conditions especially photosensitive ones and others that involve inflammation. Feb 19, 2020 In patients of Asian descent, it is recommended that visual field testing be performed in the central 24 degrees instead of the central 10 degrees. It is recommended that hydroxychloroquine be discontinued if ocular toxicity is suspected and the patient should be closely observed given that retinal changes and visual disturbances may progress. This patient was diagnosed based on fundus exam. In the remaining 15 patients, diagnosis was based upon reproducible paracentral or central scotoma on automated visual field testing or a single abnormal HVF test combined with typical fundus changes, as per diagnostic criteria of Bernstein.