Plaquenil and visual field testing

Discussion in 'Cheap And Quality Drugs' started by Vitaliy L., 17-Mar-2020.

  1. sten567 New Member

    Plaquenil and visual field testing


    Pattern of Retinopathy: Although the locus of toxic damage is parafoveal in many eyes, Asian patients often show an extramacular pattern of damage. Dose: We recommend a maximum daily HCQ use of 5.0 mg/kg real weight, which correlates better with risk than ideal weight.

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    Find user ratings and reviews for Plaquenil oral on WebMD including side effects and drug interactions, medication effectiveness, ease of use and satisfaction The main outcomes were toxicity as determined by characteristic visual field loss or retinal thinning and photoreceptor damage. They also examined risk factors and prevalence. The study findings revealed that when hydroxychloroquine was used at doses 5mg /kg, the risk of retinopathy was 1% in the first 5 yrs. 2% in 10 yrs. 20 % after 20 yrs. Humphrey Visual Field 10-2 is sensitive at detecting subtle paracentral visual field defects and is recommended during all screening visits. SITA testing with pattern deviation plots is recommended. Wider test patterns 24-2 or 30-2 are needed for Asian patients due to the possibility of extra-macular manifestations of toxicity.

    Risk of Toxicity: The risk of toxicity is dependent on daily dose and duration of use. There are no similar demographic data for CQ, but dose comparisons in older literature suggest using 2.3 mg/kg real weight.

    Plaquenil and visual field testing

    Plaquenil Side Effects on Your Eyes and Vision, My Take on New Ocular Screening Guidelines for Plaquenil.

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  5. Paracentral scotomas have been reported prior to the associated maculopathy, so an amsler grid test or central 10-2 visual field perimetry was recommended. 2,5. Additionally, color vision––helping in the assessment of macular integrity––was recommended as an optional test.

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    Macular Society Eye screening for patients taking hydroxychloroquine. Hydroxychloroquine is a medication used to treat several conditions including rheumatoid arthritis, systemic lupus erythematosus, some skin conditions especially photosensitive ones and others that involve inflammation. Feb 19, 2020 In patients of Asian descent, it is recommended that visual field testing be performed in the central 24 degrees instead of the central 10 degrees. It is recommended that hydroxychloroquine be discontinued if ocular toxicity is suspected and the patient should be closely observed given that retinal changes and visual disturbances may progress. This patient was diagnosed based on fundus exam. In the remaining 15 patients, diagnosis was based upon reproducible paracentral or central scotoma on automated visual field testing or a single abnormal HVF test combined with typical fundus changes, as per diagnostic criteria of Bernstein.

     
  6. Volcano User

    Background: The American Academy of Ophthalmology recommendations on screening for chloroquine (CQ) and hydroxychloroquine (HCQ) retinopathy are revised in light of new information about the prevalence of toxicity, risk factors, fundus distribution, and effectiveness of screening tools. Recommendations on Screening for Chloroquine and Hydroxychloroquine. Determine risk for hydroxychloroquine retinal toxicity Optometry Times Despite Plaquenil dosing recommendations, retinal toxicity.
     
  7. MosRax Well-Known Member

    13 mg/kg (10 mg/kg base), not to exceed 800 mg (620 mg base) followed by 6.5 mg/kg (5 mg/kg base), not to exceed 400 mg (310 mg base), at 6 hours, 24 hours and 48 hours after the initial dose. Will you have Weight increased with Plaquenil - eHealthMe Common and Rare Side Effects for Plaquenil Oral Plaquenil Side Effects Common, Severe, Long Term -
     
  8. freedz Moderator

    Plaquenil - FDA prescribing information, side effects and uses Jan 01, 2020 Plaquenil ® hydroxychloroquine sulfate is a white or practically white, crystalline powder, freely soluble in water; practically insoluble in alcohol, chloroform, and in ether. The chemical name for hydroxychloroquine sulfate is 2-4-7-Chloro-4-quinolylaminopentylethylamino ethanol sulfate 11.

    Plaquenil Toxicity - Symptoms, Treatment, Risk Factors.