Hydroxychloroquine is available as the brand-name drug Plaquenil. Generic drugs usually cost less than the brand-name version. Hydroxychloroquine may be used as part of a combination therapy. Plaquenil generic and brand names Chloroquine clinical trials glioma Acute kidney failure is found among people who take Plaquenil, especially for people who are female, 50-59 old, have been taking the drug for 1 - 2 years, also take medication Enbrel, and have Osteoporosis Despite optimization of renin-angiotensin-aldosterone system RAAS inhibition, patients with immunoglobulin A nephropathy IgAN and persistent proteinuria remain at risk for kidney failure. We evaluated the efficacy and safety of hydroxychloroquine HCQ, an immunomodulator, when added to the treatment regimen of patients with IgAN. PREGNANCY AND LACTATION. Hydroxychloroquine is considered safe in all trimesters of pregnancy. Due to the high risk of flare in systemic lupus erythematosus when discontinuing this medication, continued Plaquenil use is advised in these patients during pregnancy. Small amounts of hydroxychloroquine can be found in breastmilk. Hydroxychloroquine is used to treat lupus erythematosus and rheumatoid arthritis. It isn’t fully understood how this drug works to treat lupus erythematosus or rheumatoid arthritis. That means you may need to take it with other drugs. It treats malaria by killing the parasites that cause the disease. Hydroxychloroquine and kidney Hydroxychloroquine DermNet NZ, Effects of Hydroxychloroquine on Proteinuria in IgA. Interaction between hydroxychloroquine and methotrexateChloroquine dose indiaChloroquine fas associatedPerforin ctll-2 chloroquineArthritis and hydroxychloroquine Hydroxychloroquine-takers were more likely to have higher frequencies of arthritis, malar rash and photosensitivity and less severe disease overall. On the other hand, hydroxychloroquine non-takers were more likely to be smokers and had more severe disease with higher frequencies of serositis. Protective Effect of Hydroxychloroquine on Renal Damage in.. Hydroxychloroquine Plaquenil RheumTutor. Hydroxychloroquine Oral Route Before Using - Mayo Clinic. Hydroxychloroquine is usually taken with food or milk to prevent stomach upset. The dosage and length of treatment are based on your medical condition and response to therapy. In children, dosage is also based on weight. Jan 05, 2020 Hydroxychloroquine is a well-tolerated medication for various rheumatologic and dermatologic conditions. Its main side effects are gastrointestinal upset, skin rash, headache, and ocular toxicity1. Within the eye, hydroxychloroquine can adversely impact the cornea, ciliary body, and retina1 Plaquenil hydroxychloroquine is considered an older DMARD disease modifying anti-rheumatic drug. Plaquenil was actually first classified as an antimalarial drug, but it is also used to treat certain rheumatic and autoimmune conditions which are unrelated to malaria.