Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking chloroquine: Incidence not known Some side effects of chloroquine may occur that usually do not need medical attention. How to make hydroxychloroquine at home Hydroxychloroquine alternatives Hydroxychloroquine and phototherapy combination morphea Side effects of chloroquine ncbi Chloroquine is a highly effective schizontocide, while primaquine has weaker asexual-stage activity 3 but is the only generally available drug with hypnozoitocidal properties, i.e. it kills dormant liver stage parasites and prevents relapse radical cure 1. Primaquine is active as a chloroquine-resistance reverser at concentrations that could be clinically relevant. As primaquine and chloroquine are already used together in the treatment of P. vivax, this is potentially a cheap way of reviving and extending the life of chloroquine. Before the administration of chloroquine, the patient had only a mild skin erythema in the irradiated area, which was consistent with the radiotherapy dose she had received. On day 3 of chloroquine therapy, she developed localized brisk bullous eruptions in the irradiated area, which developed into a patch of fulminant moist desquamation. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Primaquine vs chloroquine The effect of chloroquine dose and primaquine on Plasmodium., Chloroquine and primaquine combining old drugs as a new. Assay of chloroquine phosphate Chloroquine combined with primaquine has been the standard radical curative regimen for Plasmodium vivax and Plasmodium ovale malaria for over half a century. In an open-label crossover pharmacokinetic study, 16 healthy volunteers 4 males and 12 females. Pharmacokinetic Interactions between Primaquine and Chloroquine. Chloroquine Side Effects Common, Severe, Long Term.. Primaquine - Wikipedia. Primaquine is a synthetic, 8-aminoquinoline derivative with antimalarial properties. Although its mechanism of action is unclear, primaquine bind to and alter the properties of protozoal DNA. This agent eliminates tissue exo-erythrocytic malarial infection, preventing the development of the erythrocytic forms. Primaquine is used after other medications such as chloroquine have killed the malaria parasites living inside red blood cells. Primaquine then kills the malaria parasites living in other body tissues. This prevents the return of the infection. Both drugs are needed for a complete cure. DHA-PQP vs Chloroquine and Primaquine for Radical Cure of Vivax Malaria in Brazil CuraVivax The safety and scientific validity of this study is the responsibility of the study sponsor and investigators.