Hydroxychloroquine in lupus pregnancy.

Discussion in 'Chloroquine Online' started by ApLex, 05-Mar-2020.

  1. ANLAIN XenForo Moderator

    Hydroxychloroquine in lupus pregnancy.


    This information should not take the place of medical care and advice from your healthcare providers. Hydroxychloroquine is a medication used to prevent and treat malaria and to treat autoimmune conditions such as rheumatoid arthritis or lupus.

    Plaquenil liquid form Hydroxychloroquine abbreviation Plaquenil drug assistance program Chloroquine in hepatic dysfunction

    OBJECTIVE To study maternal and fetal outcome of pregnancy in patients with lupus who were exposed to hydroxychloroquine HCQ. Hydroxychloroquine HCQ is often needed to manage disease activity in systemic lupus erythematosus SLE during pregnancy. The purpose of this study was to examine lupus activity and pregnancy outcomes in women with SLE treated or not treated with HCQ during pregnancy. Clowse et al. found that women who stopped taking HCQ had increased lupus activity and increased lupus flares during pregnancy. High activity lupus was defined as a physician's estimate of activity PEA greater than 2 occurred in twice as many pregnancies in which HCQ treatment was stopped as in those in which HCQ was continued.

    For more information on rheumatoid arthritis or lupus in pregnancy please see the Mother To Baby fact sheet on those topics at: https://mothertobaby.org/fact-sheets/rheumatoid-arthritis/pdf or https://mothertobaby.org/fact-sheets/lupus-pregnancy/pdf/. Hydroxychloroquine is sold under several brand names, including Plaquenil®.

    Hydroxychloroquine in lupus pregnancy.

    Hydroxychloroquine Use in Lupus Patients during Pregnancy., Hydroxychloroquine in lupus pregnancy - Clowse - 2006.

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  7. Hydroxychloroquine is an antimalarial drug. It treats malaria by killing the parasites that cause the disease. It isn’t fully understood how this drug works to treat lupus erythematosus or.

    • Hydroxychloroquine Side Effects, Dosage, Uses, and More.
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    These medications may also prevent lupus from spreading to certain organs, such as the kidney and central nervous system your brain and spinal cord and may help to reduce flares by as much as 50%. Plaquenil and other anti-malarials are the key to controlling lupus long term, and some lupus patients may be on Plaquenil for the rest of their lives. Detailed Hydroxychloroquine dosage information for adults and children. Includes dosages for Rheumatoid Arthritis, Systemic Lupus Erythematosus, Malaria Prophylaxis and more; plus renal, liver and dialysis adjustments. Women with rheumatic diseases, including inflammatory arthritis and systemic lupus erythematosus SLE, fare better in pregnancy when their disease is under good control1,2. The role of hydroxychloroquine HCQ for achieving this control is now recognized.

     
  8. as2d New Member

    Chloroquine has long been used in the treatment or prevention of malaria from Plasmodium vivax, P. malariae, excluding the malaria parasite Plasmodium falciparum, for it started to develop widespread resistance to it. Chloroquine, an old malaria drug, may help treat novel. Chloroquine - FDA prescribing information, side effects. Chloroquine - Wikipedia
     
  9. ChatJokey Jokey Moderator

    Background: The American Academy of Ophthalmology recommendations on screening for chloroquine (CQ) and hydroxychloroquine (HCQ) retinopathy are revised in light of new information about the prevalence of toxicity, risk factors, fundus distribution, and effectiveness of screening tools. Protecting your eyesight when taking Plaquenil Lupus. Hydroxychloroquine Retinopathy Still Alive and Well - The. Plaquenil-Induced Toxic Maculopathy - Decision-Maker PLUS
     
  10. HUTOR User

    On the Mechanism of Chloroquine Resistance in Plasmodium. Cooper RA, Lane KD, Deng B, Mu J, Patel JJ, et al. 2007 Mutations in transmembrane domains 1, 4 and 9 of the Plasmodium falciparum chloroquine resistance transporter alter susceptibility to chloroquine, quinine and quinidine. Mol Microbiol 63 270–282. View Article Google Scholar 18.

    Mutations in the Plasmodium falciparum chloroquine.