HI-dose Naloxone (10mg) has reversed the clinical effects of non-opiate drugs such as clonidine and ACEI. There are many theories as to why this reversal occurs. Naloxone impacts both opiate and non-opiate receptors. The following explains naloxone reversal of somnolence/hypotension due to its effects on the opiate receptors. Naloxone also has effects on other receptors (such as imidazoline) that also play a part. There are both responders and non-responders to hi-dose naloxone, but that is a question for another day. HI dose naloxone (10mg) is usually required for the reversal (one of the reasons subsequently explained). Excipient information presented when available (limited, particularly for generics); consult specific product labeling. Tablet:0.1: Clonidine hydrochloride 0.1 mg and chlorthalidone 15 mg [DSC]0.2: Clonidine hydrochloride 0.2 mg and chlorthalidone 15 mg [DSC]0.3: Clonidine hydrochloride 0.3 mg and chlorthalidone 15 mg [DSC] Treatment of hypertension Hypersensitivity to chlorthalidone or other sulfonamide-derived drugs Note: Although the FDA approved product labeling states this medication is contraindicated with other sulfonamide-containing drug classes, the scientific basis of this statement has been challenged. Hypertension: Oral: One tablet (clonidine 0.1 to 0.3 mg/chlorthalidone 15 mg per tablet) 1 to 2 times daily; maximum: 0.6 mg clonidine and 30 mg chlorthalidone daily May benefit from lower initial dose; see individual agents. No specific dosage adjustments provided in manufacturer's labeling; use with caution in severe renal disease. Ajmaline: Sulfonamides may enhance the adverse/toxic effect of Ajmaline. No specific dosage adjustments provided in manufacturer's labeling; use with caution. Specifically, the risk for cholestasis may be increased. Monitor therapy Alcohol (Ethyl): CNS Depressants may enhance the CNS depressant effect of Alcohol (Ethyl). Monitor therapy Alcohol (Ethyl): May enhance the orthostatic hypotensive effect of Thiazide and Thiazide-Like Diuretics. Monitor therapy Alfuzosin: May enhance the hypotensive effect of Blood Pressure Lowering Agents. What amoxicillin treats Doxycycline 100mg acne ACE inhibitors or angiotensin-converting enzyme inhibitors are a group of drugs used primarily for the treatment of hypertension high blood pressure and congestive heart failure. Originally synthesized from compounds found in pit viper venom, they inhibit angiotensinconverting enzyme ACE. Clonidine is not an ACE inhibitor. It is used for lowering blood pressure and has other uses as result is the same, inhibition of vasoconstrictive properties of angiotensin I and reduction in blood pressure. What is the best Ace Inhibitor? I need to add something else to the mix to get better control of my bp. I am very sensitive to drugs and have really been thru alot. I need to add something else to the mix to get better control of my bp. For high blood pressure: benazepril, enalapril, and lisinopril For heart failure: enalapril, captopril After a heart attack: lisinopril For diabetics: ramipril (Altace) For people with kidney disease: benazepril, ramipril (Altace) Four of these medicines are low-cost or moderately priced generics. I am very sensitive to drugs and have really been thru alot. I have already tried the diuretics and they made my heart race real bad. All have been proven to be just as effective as or superior to other ACEIs. One Best Buy - ramipril (Altace) - is a brand-name drug for which no generic copy is yet available. Personally, I would start with either the lisinopril or captopril and hope I wouldn't cough. (For me they are OUT because I couughed my head off with enalapril when it was the only ACE (Vasotec.) Diabetics would probably be wise to start with the higher priced Altace. Cassiebel or Lenin: Are you saying that the ACE's make your heart race? Too bad I can't handle Beta Blockers because I know they slow the heart rate down. I tried a Beta Blocker with Clonidine and I was like a zombie. I get really depressed because I am so addicted to the Clonidine. First of all, here's a website Re: Clonidine you should look at [url] Oral.aspx? VALSARTAN AND IRBESARTAN RECALLS Certain blood pressure medications that contain either valsartan or irbesartan have been recalled. If you take either of these drugs, talk to your doctor about what you should do. High blood pressure can lead to many serious health problems, such as heart attack, heart failure, stroke, and kidney disease. Treating high blood pressure early is important in preventing these and other problems. Dozens of different medications can help treat high blood pressure. They’re divided into many different categories, each of which works differently and causes different side effects. With so many options available, finding the best one for you may take some time and patience. Your doctor will work with you to find the best treatment plan for you, which may include one or more medications. Is clonidine an ace inhibitor DEA, Drug Enforcement Agency and pharmacy Techs, Is clonidine a ace inhibitor Sildenafil generic reviews ACE inhibitors angiotensin converting enzyme inhibitors and beta blockers are used to treat high blood pressure hypertension and related cardiovascular problems. Dangerous elevations in blood pressure may occur when clonidine Catapres is combined with a beta blocker, or when clonidine. ACE Inhibitors vs. Beta Blockers Facts & Side Effects. What is the best Ace Inhibitor? - High & Low Blood Pressure.. ACE Inhibitors vs. Beta Blockers Facts & Side Effects for.. How does naloxone work to reverse the effects of ACE inhibitor toxicity? HI-dose Naloxone 10mg has reversed the clinical effects of non-opiate drugs such as clonidine and ACEI. There are many theories as to why this reversal occurs. Clonidine is the generic name of Catapres, a medication used to treat high blood pressure. Clonidine works by slowing down your heart rate and relaxing blood vessels. You can take clonidine alone. Answer No, Clonidine is not an ACE inhibitor. Clonidine is a high blood pressure medication.