These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Drug interactions plaquenil Hydroxychloroquine stomach bleeding Unusual bleeding or bruising unusual facial expressions unusual tiredness or weakness yellow eyes or skin Symptoms of overdose. Drowsiness dry mouth increased thirst loss of appetite mood changes no pulse or blood pressure numbness or tingling in the hands, feet, or lips unconsciousness Jan 23, 2011 Update-as we all suspected the Rheuma says no need to stop Plaquenil however the gynae's sec said he was adamant when she spoke to him gynae surgeon last Thursday that I should stop-she said he mentioned something about bleeding excessively. He was supposed to call me on Friday but didn't. Jul 27, 2017 Breakthrough bleeding is when menstrual bleeding occurs between periods. It can be light spotting or just as heavy as your typical period. This can happen when taking an oral contraceptive. This can become a very frustrating problem for women on the pill, because one of the reasons they may be taking it in the first place is to regulate their cycles. If you notice any other effects, check with your healthcare professional. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Other side effects not listed may also occur in some patients. Plaquenil bleeding Perioperative Management of Medications Used in the Treatment., Stopping Plaquenil before surgery Lupus Forums at The Lupus. When was chloroquine invented Increased Risk of Bleeding is #650 concern in Plaquenil discussions. Plaquenil is an arthritis medication and an anti infectious agent. Uses Plaquenil is prescribed for Lupus, RA, Sjogren's Syndrome and Joint Pain and is mostly mentioned together with these indications. Can Plaquenil cause Increased Risk of Bleeding?. What Are the Causes of Breakthrough Bleeding While on Birth.. Can Plaquenil cause Rectal Bleeding? - Treato. Hallucinations, seizures, and hearing loss are among the serious side effects of Plaquenil. This eMedTV Web page provides a more in-depth list of potentially dangerous reactions and explains when to report such problems to your doctor. View detailed reports from patients taking plaquenil who experienced vaginal haemorrhage. Reports are from official medical reports as well as online extractions from user reviews and forum discussions. Hydroxychloroquine oral tablet is available as a brand-name drug and a generic drug. Brand name Plaquenil. Hydroxychloroquine comes only as a tablet you take by mouth. Hydroxychloroquine is used to treat malaria, lupus erythematosus, and rheumatoid arthritis.