It seems to me the cure is worse then the condition! Hi im starting plaquenil 200mg twice a day was wondering how far apart should the dose, be and best times to take it ,what are some of the side effects anyone has had and how long did it take to start working thank u You take plaquenil twice a day, approximately 12 hours apart. Plaquenil making hair fall out Plaquenil scleraderma Plaquenil oral side effects Nov 12, 2009 Please don't stop your plaquenil until you are sure it is the right thing to do and in your best interest. I am on plaquenil but also experience some of the same things you do. There are other meds that can help with what you are experiencing, and if your doctor didn't address that then I would seek out a second opinion. or maybe another. Hi I was told to wean my self onto Plaquenil slowly with only half a tablet every other day to begin with and to always take it with food. It took me about a month to get onto a dose of 200mg a day. 200 didn't seem to make much difference so I was told to 'up it' to 400mg a day and it took me another month to taper up to that. With Plaquenil, however, the most commonly prescribed anti-malarial, this sort of damage occurs only in 1 out of 5,000 people who take the drug for five years or more. For this reason though, it is important that you see an ophthalmologist for an exam before starting to take an anti-malarial medication for your lupus. You can take it with food if it upsets your stomach. The most common side effect is mild nausea and occasional stomach cramps. Best way to take plaquenil Hydroxychloroquine Oral Route Proper Use - Mayo Clinic, How do you take Plaquenil? - Sjogren's World Does plaquenil cause high cholesterolPlaquenil for rosacea Ive just been diagnosed and put on 400mg of Plaquenil but now I feel worse. I find the best way is to try and identify the foods or food-groups that trigger my. Ive just been diagnosed and put on 400mg of Plaquenil but now.. Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus.. Had to stop taking Plaquenil -. I understand these may go away. Is there anything I can do to reduce these symptoms? I always take the Plaquenil with a meal. Answer. You might try starting at 1/2 a tablet and work your way up slowly. Also, generic plaquenil hydroxychloroquine is often associated with more GI side effets than the name brand. Hi Guys, I haven't been here for a while - just checked in and found this question on Plaquenil - for me it took approx nine weeks to begin to work - I'm only taking 200mg per day so far - it seemed to stop working a few weeks later - most days are pretty good I s'pose but I drop nearly every afternoon. Plaquenil is a slow acting drug and most people dont notice any difference in the way they feel for at least a month. It takes up to 3 months to build up in your body and actually start to make a difference in your blood work and symptoms. Most rheumy's will give plaquenil along with prednisone to boost/quicken the anti-inflamitory process.