Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. What is the half life of chloroquine Thrombocytopenia plaquenil Plaquenil side effects mood changes Hydroxychloroquine Plaquenil® When hydroxychloroquine is used with other medications it can be used to treat some auto-immune diseases. Doctors will use hydroxychloroquine to treat auto-immune diseases when other medications have not been successful or a patient cannot be on those medications. Plaquenil Hydroxychloroquine is used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus & others. Hydroxychloroquine Plaquenil, chloroquine Aralen, and quinacrine Atabrine are medications that were originally used to prevent or treat malaria. However, during World War II it was also found that these medications were effective in treating the symptoms of lupus. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. Hydroxychloroquine immunosuppressant Hydroxychloroquine and the immune system Hi everyone. - NRAS, Plaquenil Hydroxychloroquine - Side Effects, Dosage. Tbe chloroquine gelChloroquine plus primaquineIntermittent preventive therapy chloroquinePlaquenil and sleChloroquine target cycle Hydroxychloroquine is an aminoquinoline like chloroquine. It is a commonly prescribed medication in the treatment of uncomplicated malaria, rheumatoid arthritis, chronic discoid lupus erythematosus, and systemic lupus erythematosus. Hydroxychloroquine is also used for the prophylaxis of malaria in regions where chloroquine resistance is unlikely. Hydroxychloroquine - DrugBank. Treating Lupus with Anti-Malarial Drugs Johns Hopkins.. Hydroxychloroquine Plaquenil. Rheumatoid Arthritis. The action of hydroxychloroquine is cumulative and may require weeks to months to achieve the maximum therapeutic effect see CLINICAL PHARMACOLOGY. Initial adult dosage 400 mg to 600 mg 310 to 465 mg base daily, administered as a single daily dose or in two divided doses. Hydroxychloroquine Plaquenil Is an Immunosuppressant. In my opinion, Plaquenil is best considered an immunosuppressant. It’s true that it’s different than other immunosuppressants like methotrexate or cyclosporine. It does not seem to predispose to cancer development but does predispose to some infections. Two studies have shown that shingles herpes zoster is increased in hydroxychloroquine users. Hydroxychloroquine HCQ, a lysosomotropic amine, is an immunosuppressive agent presently being evaluated in bone marrow transplant patients to treat graft-versus-host disease. While its immunosuppressive properties have been attributed primarily to its ability to interfere with antigen processing, recent reports demonstrate HCQ also blocks T-cell activation in vitro.