Chloroquine action

Discussion in 'International Pharmacy' started by peratruper, 21-Feb-2020.

  1. Chloroquine action


    Inhibition of protein synthesis is also observed, evidently as a secondary effect. Inhibition of DNA replication is proposed as a general mechanism of the antimicrobial action of chloroquine.

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    Chloroquine works best when you take it on a regular schedule. For example, if you are taking it once a week to prevent malaria, it is best to take it on the same day of each week. Make sure that you do not miss any doses. If you have any questions about this, check with your doctor. Mechanism of Action Chloroquine, a 4-aminoquinoline, is an anti-protozoal agent. The precise mechanism by which Chloroquine exhibits activity is not known. Chloroquine, may exert its effect against Plasmodium species by concentrating in the acid vesicles of the parasite and by inhibiting polymerization of heme. It can also inhibit certain. Find patient medical information for Chloroquine Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.

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    Chloroquine action

    Chloroquine Oral Uses, Side Effects, Interactions., Chloroquine - FDA prescribing information, side effects and uses

  2. Plaquenil and kidneys
  3. Chloroquine binds to heme or FP to form what is known as the FP-Chloroquine complex; this complex is highly toxic to the cell and disrupts membrane function. Action of the toxic FP-Chloroquine and FP results in cell lysis and ultimately parasite cell autodigestion. In essence, the parasite cell drowns in its own metabolic products.

    • Chloroquine C18H26ClN3 - PubChem.
    • Chloroquine Oral Uses, Side Effects, Interactions, Pictures..
    • Chloroquine - Wikipedia.

    Mechanism of Action Chloroquine, a 4-aminoquinoline, is an anti-protozoal agent. The precise mechanism by which Chloroquine exhibits activity is not known. Chloroquine, may exert its effect against Plasmodium species by concentrating in the acid vesicles of the parasite and by inhibiting polymerization of heme. It can also inhibit certain enzymes by its interaction with DNA. Pharmacol Ther. 1993 Feb-Mar;572-3203-35. Chloroquine mechanism of drug action and resistance in Plasmodium falciparum. Slater AF1. Of note, chloroquine and hydroxychloroquine are considered to be safe and side-effects are generally mild and transitory. However, the margin between the therapeutic and toxic dose is narrow and chloroquine poisoning has been associated with cardiovascular disorders that can be life-threatening Frisk-Holmberg et al. 1983. Chloroquine and.

     
  4. Dimarik Moderator

    DISCLAIMER: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects. CBD and Drug Interactions An Easy Guide - CBD School Chloroquine phosphate and Ibuprofen drug interactions.
     
  5. Yoshimoto Moderator

    Chloroquine Uses, Side Effects & Warnings - Parasites that cause malaria typically enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Chloroquine is used to treat and to prevent malaria. Chloroquine is also used to treat amebiasis infection caused by amoebae.

    Chloroquine phosphate C18H32ClN3O8P2 - PubChem