Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Taking chloroquine and trazodone Oct test for plaquenil Plaquenil renal toxicity Hydroxychloroquine should be taken with a meal or a glass of milk to minimise the gastrointestinal side effects. Alternate-day dosing can be used. For example, hydroxychloroquine 400 mg alternating with hydroxychloroquine 200 mg daily can be used to reach effective daily dosing of 300 mg/day. Side Effects. Continuing ringing or buzzing or other unexplained noise in the ears. feeling of constant movement of self or surroundings. irritability. nausea. nervousness. nightmares. sensation of spinning. shakiness and unsteady walk. uncontrolled eye movements. unsteadiness, trembling, or other. Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Hydroxychloroquine rare side effects Plaquenil Side Effects Common, Severe, Long Term -, Hydroxychloroquine Oral Route Side Effects - Mayo Clinic Chloroquine nuclei acid biosynthesisChloroquine lysosomal accumualtionPlaquenil pill dosesMeds for lupus plaquenil generic name Serious side effects and their symptoms can include the following blurred vision or other vision changes. ringing in your ears or hearing loss. angioedema, or rapid swelling of your skin. hives. mild or severe bronchospasm that causes trouble breathing. sore throat. unusual bleeding or bruising. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Hydroxychloroquine Plaquenil Side Effects & Dosage for.. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Other rare side effects include changes in skin pigmentation and cardiomyopathy diseases of the heart muscle. The future Hydroxychloroquine was previously prescribed only for people whose lupus disease activity was mild in its course; if the lupus became active, steroids or immunosuppressants would be prescribed instead. Hydroxychloroquine typically is very well tolerated. Serious side effects are rare. The most common side effects are nausea and diarrhea, which often improve with time. Less common side effects include rash, changes in skin pigment such as darkening or dark spots, hair changes, and muscle weakness. Rarely, hydroxychloroquine can lead to anemia in Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.