These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Hydroxychloroquine alopecia Plaquenil eye exam letter review of optometry I have read about people stopping P & flaring up. Those who stopped it abruptly had real problems similar to what you are experiencing. If you really need to get off it, I would taper down slowly, very slowly. There is a similar posting on Healthunlocked, "Why oh why did u stop taking plaquenil." You may want to check it out. Plaquenil is a 6-weeker as far as the benefits are concerned, but it would be more dangerous to stop if you spend a lot of time outside and if this were the summer. If you're gonna experiment, I went off it cold turkey as it didn't hurt to do it that way, but you better get back on before the summer or you could experience a flare-up. Although they are uncommon, Plaquenil has side effects that may affect your eyes. Plaquenil and Your Eyes In some people, Plaquenil can cause a condition called hydroxychloroquine retinopathy, often referred to as bulls-eye maculopathy. If you notice any other effects, check with your healthcare professional. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Other side effects not listed may also occur in some patients. Stopping plaquenil effects Plaquenil Oral Uses, Side Effects, Interactions., What is the correct way to discontinue use of plaquenil? Does hydroxychloroquine affect the kidneysPlaquenil steroids I had to stop Plaquenil after a few days. I couldn't walk, was dizzy, my speech was slurred, blurry vision, etc. but, I'm the one who usually gets side effects. I know people who Plaquenil has worked wonders. The side effects cleared up within a week. I also have Sjorgens, and my eyes were dryer on Plaquenil, but the blurry vision was the worst. Stopping Plaquenil? DailyStrength. Plaquenil Side Effects on Your Eyes and Vision. Will you have Withdrawal syndrome with Plaquenil - eHealthMe. Plaquenil can cause serious side effects when used in high doses for chronic diseases such as RA over the long term. The New Zealand Dermatological Society recommends that to decrease the risk of retina damage, no more than 200mg of Plaquenil should be taken a day, and a dose of 400mg per day should be taken no longer than a few weeks. In Stop Sarcoidosis My pulmonist started me on high doses of prednisone in 1999, he would start to decrease, and he would tell me I am not responding to the decrease. Methotrexate and side effects In Stop Sarcoidosis Have just had my second dose of methotrexate and have had side effects already. Common side effects may include headache, dizziness, ringing in your ears; nausea, vomiting, stomach pain; loss of appetite, weight loss; mood changes, feeling nervous or irritable; skin rash or itching; or. hair loss.