When should prophylactic chloroquine be taken

Discussion in 'Online Canadian Pharmacy' started by Extrally, 05-Mar-2020.

  1. AlexBG New Member

    When should prophylactic chloroquine be taken

    I would appreciate feedback on the reasoning outlined below. I have convinced myself that it makes sense, but am looking for independent feedback and have been struggling to get it.

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    Chloroquine should be started for prophylaxis one to two weeks before potential exposure, is taken weekly, and must be continued for four weeks after your trip. Blood Stage Prophylaxis In Vivax Malaria. Blood stage prophylaxis is the most common type of prophylaxis in use. Chloroquine, was the first drug in this group to be extensively used. It was introduced in the early 1950’s for the prevention of both falciparum and vivax malaria. Chloroquine phosphate comes as a tablet to take by mouth. For prevention of malaria in adults, one dose is usually taken once a week on exactly the same day of the week. Your doctor will tell you how many tablets to take for each dose.

    , etc.), or provide argument why this is a dumb idea. I would greatly appreciate it if someone could knit-pick this with a fine tooth comb and try and find some mistake I've made (off by a order of magnitude?

    When should prophylactic chloroquine be taken

    Chloroquine when to start taking – Crewbane Solutions, Prophylaxis of Malaria - PubMed Central PMC

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  6. When chloroquine, doxycycline, or mefloquine is used for primary prophylaxis, primaquine is usually taken during the last 2 weeks of postexposure prophylaxis. When atovaquone-proguanil is used for prophylaxis, primaquine may be taken during the final 7 days of atovaquone-proguanil, and then for an additional 7 days.

    • Malaria - Chapter 4 - 2020 Yellow Book Travelers' Health..
    • Chloroquine MedlinePlus Drug Information.
    • Chloroquine & Proguanil Anti-Malarial Tablets.

    The steady-state serum concentration of 500mg of CQ taken once weekly is 0.1uM,12 which given the above reasoning, would be expected to lead to a lung concentration above the reported EC90 of SARS-CoV-2. 500mg of CQ taken once weekly is the malaria prophylaxis dose of CQ. This dose is extremely well-tolerated with minimal side-effects in most. Jul 23, 2014 The standard treatment course should be completed and antimalarial chemoprophylaxis commenced one week after taking the first treatment dose, except in the case of mefloquine prophylaxis, which should be resumed at least twelve hours after the last treatment dose if quinine was used for standby treatment. Chloroquine has not been shown to have any harmful effects on the fetus when used for malarial prophylaxis. Small amounts of chloroquine are excreted in the breast milk of lactating women. However, because this drug can be safely prescribed to infants, the effects are not harmful.

  7. q2w Moderator

    Chloroquine is used to prevent or treat malaria caused by mosquito bites in countries where malaria is common. Chloroquine Uses, Side Effects & Warnings - What Is the Life Cycle of Malaria? New Health Advisor Treatment_of_malaria TUSOM Pharmwiki
  8. Gaas Moderator

    Common and Rare Side Effects for Plaquenil Oral Find information about common, infrequent and rare side effects of Plaquenil Oral.

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  9. Andrey42 Well-Known Member

    Focus on Eyes Long-term Plaquenil intake can affect your vision Feb 20, 2018 Focus on Eyes Long-term Plaquenil intake can affect your vision. Taking high doses or long-term treatment of Plaquenil, an anti-malaria drug used to treat lupus, can lead to vision problems.

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