Plaquenil use with retinopathy

Discussion in 'Plaquenil 200mg' started by ma-x-us, 17-Mar-2020.

  1. polina XenForo Moderator

    Plaquenil use with retinopathy


    Pattern of Retinopathy: Although the locus of toxic damage is parafoveal in many eyes, Asian patients often show an extramacular pattern of damage. Dose: We recommend a maximum daily HCQ use of 5.0 mg/kg real weight, which correlates better with risk than ideal weight.

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    Studies have shown that patients who have manifested with retinopathy have traces of Plaquenil metabolites in their erythrocytes, plasma, and urine even after 5 years of discontinuing the medication 1, 2, 3. HCQ is widely used for the treatment of rheumatic diseases, particularly lupus and RA. It is generally well tolerated, but retinopathy is a concern. Retinopathy is rare, but is sight threatening, generally irreversible and may progress even after cessation of therapy. Damage may be subclinical. Hydroxychloroquine, sold under the brand name Plaquenil among others, is a medication used for the prevention and treatment of certain types of malaria. Specifically it is used for chloroquine-sensitive malaria. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda. It is taken by mouth. Common side effects include vomiting, headache, changes in vision and muscle weakness. Severe side effects may include allergic reactions. It does not appear to be safe during

    Risk of Toxicity: The risk of toxicity is dependent on daily dose and duration of use. There are no similar demographic data for CQ, but dose comparisons in older literature suggest using 2.3 mg/kg real weight.

    Plaquenil use with retinopathy

    Plaquenil Uses, Dosage & Side Effects -, Hydroxychloroquine-related retinal toxicity Rheumatology.

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  7. While side effects of corticosteroids are usually to blame, there is also the possibility of ocular damage associated with long-term use of the antimalarial drugs hydroxychloroquine brand name Plaquenil® and chloroquine. Improved vision screening tests and updated dosing guidelines are key to avoiding such complications.

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    Diagnosis Hydroxychloroquine-induced retinal toxicity Discussion. Chloroquine CQ and hydroxychloroquine Plaquenil HCQ have been used for many years, initially for the treatment of malaria but now more commonly for the treatment of inflammatory diseases such as rheumatoid arthritis and lupus 1. It is now considered for new disease applications in diabetes, heart disease and adjunct cancer therapies 2. H ydroxychloroquine HCQ; Plaquenil, Sanofi, Bridgewater, NJ is an antimalarial agent that is also commonly used as a treatment for a variety of rheumatologic and dermatologic conditions, such as rheumatoid arthritis and systemic lupus erythematosus. The most common side effect associated with its use is retinal toxicity, which may be irreversible. Use of Plaquenil is contraindicated in patients with known hypersensitivity to 4-aminoquinoline compounds. Warnings Resistant strains of malaria Plaquenil is not effective against chloroquine-resistant strains of P. falciparum see CLINICAL PHARMACOLOGY – Microbiology.

     
  8. dekormaster Moderator

    Plaquenil (hydroxychloroquine) belongs to a group of medicines called quinolines. Plaquenil Side Effects on Your Eyes and Vision Alternatives to Plaquenil DailyStrength Diagnostic Tests for Sjogren's Syndrome -
     
  9. maldimon Moderator

    Is it safe to take amoxicillin with hydroxychloroquine? - Answers You can take Advil or another NSAID while taking Plaquenil hydroxychloroquine as long as NSAID isn't contraindicated for you. Asked in Health, Medication and Drugs, Antibiotics, Xanax.

    Plaquenil, Imuran, Probiotics. Oh My! - Inspire