Part of that is due to less exercise, part due to having no appetite thus feeling like anything I can get down is ok. Well, now I've been exercising at almost my pre-Lupus rate (ran a marathon a year before), eating a more moderate diet (clean protein, vegs & fruits), and am no longer taking that weight & bloat causing Prednisone (off Pred almost 2 yrs now). My question: Do you feel like you've gained weight on Plaquenil (ie without Prednisone)? Lupus treatment hydroxychloroquine Hydroxychloroquine nursing implications Plaquenil and losing eyelashes Chloroquine sleep Hence, if the loss of appetite and weight loss started after you started on this drug, then yes, it could be due to Plaquenil. However, if you had loss of appetite and weight loss before your started this drug, then the drug can aggravate the process. In this case, the cause of loss f appetite and weight loss has to be found. Sep 13, 2019 Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Although not all of these side effects may occur, if they do occur. These are appropriate only if major organ involvement isn't present. Plaquenil is the newest & safest in the class. The drug helps with skin rashes, hair loss, mouth ulcers, joint pain & swelling, fatigue, etc. It takes perhaps 3-4 months to build up & reach full effect. GOOD NEWS hair loss & weight gain are NOT associated with Plaquenil. My Lupus has been really quiet for about 2 yrs, and I'm afraid to change anything. The Plaquenil drug side effects list weight loss, but some people have reported weight gain instead. My rheumy wants me to come down and then off my Plaquenil, but I've been resisting simply because I'm afraid to. Weight loss plaquenil Plaquenil Oral Uses, Side Effects, Interactions., Plaquenil Side Effects Common, Severe, Long Term - Plaquenil shortage 2017 Hydroxychloroquine received an overall rating of 7 out of 10 stars from 368 reviews. See what others have said about Hydroxychloroquine, including the effectiveness, ease of use and side effects. Hydroxychloroquine Reviews Everyday Health. Want to know good stuff about plaquenil - HealthBoards. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Can Plaquenil cause Weight Loss? Weight Loss is a known side effect of Plaquenil. Complete analysis from patient reviews and trusted online health resources, including first-hand experiences. A risk factor for Plaquenil hydroxychloroquine retinotoxicity is a daily dose that exceeds 5.0 mg of drug per kg of body weight. The tool on the right simply calculates this threshold based on a ppatient’s real body weight. It’s important to understand that the daily dose is only one risk factor for plaquenil retinotoxicity. Just wondering if anyone else had problems with loss of appetite and weight loss while on plaquenil. I had my dose increased to 400mg a day about three weeks ago, and since then I have no appetite whatsoever. Weight is falling off me at a rather alarming rate - at least half a stone a week.