Additionally, another exception occurred while executing the custom error page for the first exception. Applies to hydroxychloroquine: oral tablet Along with its needed effects, hydroxychloroquine (the active ingredient contained in Plaquenil) may cause some unwanted effects. Hydroxychloroquine sulfate vs hydroxychloroquine Plaquenil skin cha ges Plaquenil and Weight loss - from FDA reports Summary Weight loss is found among people who take Plaquenil, especially for people who are female, 50-59 old, have been taking the drug for 5 - 10 years, also take medication Enbrel, and have Pain. Weight loss is found among people who take Hydroxychloroquine sulfate, especially for people who are female, 2-9 old, have been taking the drug for 1 - 2 years, also take medication Enbrel, and have Juvenile rheumatoid arthritis Plaquenil can cause loss of appetite and I agree that losing weight at this rate and suffering diarrhea is not healthy and might mean you become ill nourished and dehydrated. I suggest lowering the dose, going back to the original, until your tum has settled down then very gradually increasing it to give your body the maximum chance to adjust. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Although not all of these side effects may occur, if they do occur they may need medical attention. Will plaquenil cause weight loss Hair loss and Plaquenil? DailyStrength, Will you have Weight loss with Hydroxychloroquine sulfate. Chloroquine resistant malaria in indiaCan plaquenil cause low blood pressure Doctors give unbiased, trusted information on whether Plaquenil can cause or treat Weight Gain Dr. Valdez on hydroxychloroquine and weight gain Depression can cause weight gain and loss, but alopecia not a common sign of depression. Hydroxychloroquine and weight gain - Answers on HealthTap. Plaquenil & weight loss Lupus Forums at The Lupus Site. How good is Hydroxychloroquine, and any side effe.. Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Plaquenil is the brand name of hydroxychloroquine, a drug used to prevent or treat malaria. Plaquenil can cause serious side effects when used in high doses for chronic diseases such as RA over the long term. Plaquenil caused a loss of appitite and weight loss for me. Both times I started taking it, the first time it was so serious I had to stop taking it. Started again several years later when I flared again and had loss of appitite and weight loss but a bit more moderate.