Chloroquine and ciprofloxacin for typhoid prophylaxis

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  1. exqui Moderator

    Chloroquine and ciprofloxacin for typhoid prophylaxis


    Begin 1-2 days before travel, daily during travel, and for 7 days after leaving. 500 mg chloroquine phosphate (300 mg base) orally on the same day each week Comments: -If possible, suppressive therapy should start 2 weeks prior to exposure; if unable to start 2 weeks before exposure, an initial loading dose of 1 g chloroquine phosphate (600 mg base) may be taken orally in 2 divided doses, 6 hours apart.

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    Two typhoid vaccines are available for use in the United States 1 a Vi capsular polysaccharide vaccine for parenteral use Typhim Vi, manufactured by Sanofi Pasteur and 2 an oral live-attenuated vaccine Vivotif, manufactured from the Ty21a strain of Salmonella serotype Typhi by PaxVax. Ciprofloxacin Cipro is a prescription broad-spectrum fluoroquinolone antibiotic highly active against Gram-negative bacteria. Ciprofloxacin is a good antibiotic for traveler's diarrhea and food poisoning due to its activity against food-borne bacteria such as E. coli, Vibrio cholera, Campylobacter jejuni, Yersinia, Salmonella and Shigella. Ciprofloxacin is an inexpensive antibacterial, whereas chloroquine is an inexpensive antimalarial. The coadministration of chloroquine and ciprofloxacin is easily encountered because both drugs are.

    Approved indication: For the suppressive treatment of malaria due to Plasmodium vivax, P malariae, P ovale, and susceptible strains of P falciparum CDC Recommendations: 300 mg base (500 mg salt) orally once a week Comments: -For prophylaxis only in areas with chloroquine-sensitive malaria -Prophylaxis should start 1 to 2 weeks before travel to malarious areas; should continue weekly (same day each week) while in malarious areas and for 4 weeks after leaving such areas. -Suppressive therapy should continue for 8 weeks after leaving the endemic area.

    Chloroquine and ciprofloxacin for typhoid prophylaxis

    Travel Medicine and Vaccinations Malaria Prophylaxis, Ciprofloxacin Cipro for Food Poisoning

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  7. Summary. Aralen is the brand name for the generic drug chloroquine, an anti-malaria drug used to treat malaria and amebiasis infection that's spread outside of the intestines. Dosage, drug interactions, and pregnancy and breastfeeding safety information should be reviewed prior to taking this drug.

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    Chloroquine-resistant Plasmodium falciparum is widespread in South Asia. Issues related to malaria prophylaxis are discussed separately. Dengue fever is an arboviral disease endemic throughout much of South Enteric fever is endemic throughout most of South Asia; this area has among the highest risk for enteric fever worldwide. Antibiotic therapy is the only effective treatment for typhoid fever. Commonly prescribed antibiotics. Commonly prescribed antibiotics include Ciprofloxacin Cipro. In the United States, doctors often prescribe this for nonpregnant adults. Another similar drug called ofloxacin also may be used. Oct 01, 2018 Chloroquine taken in the dose recommended for malaria prophylaxis can reduce the antibody response to primary immunization with intradermal human diploid-cell rabies vaccine. Praziquantel In a single-dose interaction study, Chloroquine has been reported to reduce the bioavailability of praziquantel.

     
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